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Jarid2 (Jumonji, AT Rich Interactive Domain 2) Regulates NOTCH1 Expression via Histone Modification in the Developing Heart

Jarid2/Jumonji, the founding member of the Jmj factor family, critically regulates various developmental processes, including cardiovascular development. The Jmj family was identified as histone demethylases, indicating epigenetic regulation by Jmj proteins. Deletion of Jarid2 in mice resulted in ca...

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Autors principals: Mysliwiec, Matthew R., Carlson, Clayton D., Tietjen, Josh, Hung, Holly, Ansari, Aseem Z., Lee, Youngsook
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256911/
https://ncbi.nlm.nih.gov/pubmed/22110129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.315945
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