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Study of purinosome assembly in cell-based model systems with de novo purine synthesis and salvage pathway deficiencies

BACKGROUND: The enzymes involved in de novo purine synthesis (DNPS), one of the basic processes in eukaryotic cells, transiently and reversibly form a dynamic multienzyme complex called the purinosome in the cytoplasm. The purinosome has been observed in a broad spectrum of cells, but some studies c...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Baresova, Veronika, Skopova, Vaclava, Souckova, Olga, Krijt, Matyas, Kmoch, Stanislav, Zikanova, Marie
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066232/
https://ncbi.nlm.nih.gov/pubmed/30059557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201432
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