Effect of ABT-888 on the apoptosis, motility and invasiveness of BRAFi-resistant melanoma cells

Melanoma is a molecularly heterogeneous disease with many genetic mutations and altered signaling pathways. Activating mutations in the BRAF oncogene are observed in approximately 50% of cutaneous melanomas and the use of BRAF inhibitor (BRAFi) compounds has been reported to improve the outcome of p...

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Publicado en:Int J Oncol
Autores principales: Fratangelo, Federica, Camerlingo, Rosa, Carriero, Maria Vincenza, Pirozzi, Giuseppe, Palmieri, Giuseppe, Gentilcore, Giusy, Ragone, Concetta, Minopoli, Michele, Ascierto, Paolo Antonio, Motti, Maria Letizia
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2018
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065454/
https://ncbi.nlm.nih.gov/pubmed/29956724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2018.4457
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