Targeting the cross-talk between Urokinase receptor and Formyl peptide receptor type 1 to prevent invasion and trans-endothelial migration of melanoma cells

BACKGROUND: Accumulating evidence demonstrates that the Urokinase Receptor (uPAR) regulates tumor cell migration through its assembly in composite regulatory units with transmembrane receptors, and uPAR(88–92) is the minimal sequence required to induce cell motility through the Formyl Peptide Recept...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Ragone, Concetta, Minopoli, Michele, Ingangi, Vincenzo, Botti, Giovanni, Fratangelo, Federica, Pessi, Antonello, Stoppelli, Maria Patrizia, Ascierto, Paolo Antonio, Ciliberto, Gennaro, Motti, Maria Letizia, Carriero, Maria Vincenza
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721612/
https://ncbi.nlm.nih.gov/pubmed/29216889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0650-x
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