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Controversial Role of Kisspeptins/KiSS-1R Signaling System in Tumor Development
KiSS-1 was first described as a metastasis suppressor gene in malignant melanoma. KiSS-1 encodes a 145 amino-acid residue peptide that is further processed, producing the 54 amino acid metastin and shorter peptides collectively named kisspeptins (KPs). KPs bind and activate KiSS-1R (GPR54). Although...
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| Udgivet i: | Front Endocrinol (Lausanne) |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5936968/ https://ncbi.nlm.nih.gov/pubmed/29760678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00192 |
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