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The kinase activity of the channel-kinase protein TRPM7 regulates stability and localization of the TRPM7 channel in polarized epithelial cells

The channel-kinase transient receptor potential melastatin 7 (TRPM7) is a bifunctional protein with ion channel and kinase domains. The kinase activity of TRPM7 has been linked to the regulation of a broad range of cellular activities, but little is understood as to how the channel itself is regulat...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Cai, Na, Lou, Liping, Al-Saadi, Namariq, Tetteh, Sandra, Runnels, Loren W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065181/
https://ncbi.nlm.nih.gov/pubmed/29866880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001925
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