Hepatocystin is Essential for TRPM7 Function During Early Embryogenesis

Mutations in protein kinase C substrate 80K-H (PRKCSH), which encodes for an 80 KDa protein named hepatocystin (80K-H, PRKCSH), gives rise to polycystic liver disease (PCLD). Hepatocystin functions as the noncatalytic beta subunit of Glucosidase II, an endoplasmic reticulum (ER)-resident enzyme invo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Overton, Jeffrey D., Komiya, Yuko, Mezzacappa, Courtney, Nama, Kaushik, Cai, Na, Lou, Liping, Fedeles, Sorin V., Habas, Raymond, Runnels, Loren W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680877/
https://ncbi.nlm.nih.gov/pubmed/26671672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18395
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