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A potential strategy for reducing cysts in autosomal dominant polycystic kidney disease with a CFTR corrector
Autosomal dominant polycystic kidney disease (ADPKD) is associated with progressive enlargement of cysts, leading to a decline in function and renal failure that cannot be prevented by current treatments. Mutations in pkd1 and pkd2, encoding the polycystin 1 and 2 proteins, induce growth-related pat...
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| Опубликовано в: : | J Biol Chem |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6065164/ https://ncbi.nlm.nih.gov/pubmed/29875161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001846 |
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