Two polymorphic cholesterol monohydrate crystal structures form in macrophage culture models of atherosclerosis

The formation of atherosclerotic plaques in the blood vessel walls is the result of LDL particle uptake, and consequently of cholesterol accumulation in macrophage cells. Excess cholesterol accumulation eventually results in cholesterol crystal deposition, the hallmark of mature atheromas. We follow...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Varsano, Neta, Beghi, Fabio, Elad, Nadav, Pereiro, Eva, Dadosh, Tali, Pinkas, Iddo, Perez-Berna, Ana J., Jin, Xueting, Kruth, Howard S., Leiserowitz, Leslie, Addadi, Lia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2018
Gaiak:
Physical Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065044/
https://ncbi.nlm.nih.gov/pubmed/29967179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803119115
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