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Two polymorphic cholesterol monohydrate crystal structures form in macrophage culture models of atherosclerosis

The formation of atherosclerotic plaques in the blood vessel walls is the result of LDL particle uptake, and consequently of cholesterol accumulation in macrophage cells. Excess cholesterol accumulation eventually results in cholesterol crystal deposition, the hallmark of mature atheromas. We follow...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Varsano, Neta, Beghi, Fabio, Elad, Nadav, Pereiro, Eva, Dadosh, Tali, Pinkas, Iddo, Perez-Berna, Ana J., Jin, Xueting, Kruth, Howard S., Leiserowitz, Leslie, Addadi, Lia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065044/
https://ncbi.nlm.nih.gov/pubmed/29967179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803119115
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