Two polymorphic cholesterol monohydrate crystal structures form in macrophage culture models of atherosclerosis

The formation of atherosclerotic plaques in the blood vessel walls is the result of LDL particle uptake, and consequently of cholesterol accumulation in macrophage cells. Excess cholesterol accumulation eventually results in cholesterol crystal deposition, the hallmark of mature atheromas. We follow...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Varsano, Neta, Beghi, Fabio, Elad, Nadav, Pereiro, Eva, Dadosh, Tali, Pinkas, Iddo, Perez-Berna, Ana J., Jin, Xueting, Kruth, Howard S., Leiserowitz, Leslie, Addadi, Lia
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2018
Materias:
Physical Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065044/
https://ncbi.nlm.nih.gov/pubmed/29967179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803119115
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