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Two polymorphic cholesterol monohydrate crystal structures form in macrophage culture models of atherosclerosis
The formation of atherosclerotic plaques in the blood vessel walls is the result of LDL particle uptake, and consequently of cholesterol accumulation in macrophage cells. Excess cholesterol accumulation eventually results in cholesterol crystal deposition, the hallmark of mature atheromas. We follow...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6065044/ https://ncbi.nlm.nih.gov/pubmed/29967179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803119115 |
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