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Two polymorphic cholesterol monohydrate crystal structures form in macrophage culture models of atherosclerosis

The formation of atherosclerotic plaques in the blood vessel walls is the result of LDL particle uptake, and consequently of cholesterol accumulation in macrophage cells. Excess cholesterol accumulation eventually results in cholesterol crystal deposition, the hallmark of mature atheromas. We follow...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Varsano, Neta, Beghi, Fabio, Elad, Nadav, Pereiro, Eva, Dadosh, Tali, Pinkas, Iddo, Perez-Berna, Ana J., Jin, Xueting, Kruth, Howard S., Leiserowitz, Leslie, Addadi, Lia
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065044/
https://ncbi.nlm.nih.gov/pubmed/29967179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803119115
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