Pseudomonas aeruginosa LasB Subverts Alveolar Macrophage Activity by Interfering With Bacterial Killing Through Downregulation of Innate Immune Defense, Reactive Oxygen Species Generation, and Complement Activation

Pseudomonas aeruginosa (P.a) is a pathogen causing significant morbidity and mortality, in particular, in hospital patients undergoing ventilation and in patients with cystic fibrosis. Among the virulence factors secreted or injected into host cells, the physiopathological relevance of type II secre...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Bastaert, Fabien, Kheir, Saadé, Saint-Criq, Vinciane, Villeret, Bérengère, Dang, Pham My-Chan, El-Benna, Jamel, Sirard, Jean-Claude, Voulhoux, Romé, Sallenave, Jean-Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6064941/
https://ncbi.nlm.nih.gov/pubmed/30083156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01675
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