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VE-Cadherin Cleavage by LasB Protease from Pseudomonas aeruginosa Facilitates Type III Secretion System Toxicity in Endothelial Cells

Infection of the vascular system by Pseudomonas aeruginosa (Pa) occurs during bacterial dissemination in the body or in blood-borne infections. Type 3 secretion system (T3SS) toxins from Pa induce a massive retraction when injected into endothelial cells. Here, we addressed the role of type 2 secret...

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Autors principals: Golovkine, Guillaume, Faudry, Eric, Bouillot, Stéphanie, Voulhoux, Romé, Attrée, Ina, Huber, Philippe
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953407/
https://ncbi.nlm.nih.gov/pubmed/24626230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003939
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