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Pharmacological Activation of Rap1 Antagonizes the Endothelial Barrier Disruption Induced by Exotoxins ExoS and ExoT of Pseudomonas aeruginosa

Most clinical strains of Pseudomonas aeruginosa, a leading agent of nosocomial infections, are multiresistant to antibiotherapy. Because of the paucity of new available antibiotics, the investigation of strategies aimed at limiting the action of its major virulence factors has gained much interest....

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Vydáno v:Infect Immun
Hlavní autoři: Bouillot, Stéphanie, Attrée, Ina, Huber, Philippe
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399046/
https://ncbi.nlm.nih.gov/pubmed/25690098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00010-15
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