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Pharmacological Activation of Rap1 Antagonizes the Endothelial Barrier Disruption Induced by Exotoxins ExoS and ExoT of Pseudomonas aeruginosa

Most clinical strains of Pseudomonas aeruginosa, a leading agent of nosocomial infections, are multiresistant to antibiotherapy. Because of the paucity of new available antibiotics, the investigation of strategies aimed at limiting the action of its major virulence factors has gained much interest....

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Библиографические подробности
Опубликовано в: :Infect Immun
Главные авторы: Bouillot, Stéphanie, Attrée, Ina, Huber, Philippe
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399046/
https://ncbi.nlm.nih.gov/pubmed/25690098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00010-15
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