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TGF-beta signaling in cancer: post-transcriptional regulation of EMT via hnRNP E1

The TGFβ signaling pathway is a critical regulator of cancer progression in part through induction of the epithelial to mesenchymal transition (EMT). This process is aberrantly activated in cancer cells, facilitating invasion of the basement membrane, survival in the circulatory system, and dissemin...

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Détails bibliographiques
Publié dans:Cytokine
Auteurs principaux: Howley, Breege V, Howe, Philip H
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063801/
https://ncbi.nlm.nih.gov/pubmed/29396052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2017.12.032
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