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hnRNP E1 Protects Chromosomal Integrity by Translational Regulation of Cdc27

Cdc27 is a core component of the anaphase-promoting complex/cyclosome (APC/C), a multi-subunit E3 ubiquitin ligase whose oscillatory activity is responsible for the metaphase-to-anaphase transition and mitotic exit. Here, in normal murine mammary gland epithelial cells (NMuMG), Cdc27 expression is c...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Link, Laura A., Howley, Breege V., Hussey, George S., Howe, Philip H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955705/
https://ncbi.nlm.nih.gov/pubmed/27102006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0018
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