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TGF-beta signaling in cancer: post-transcriptional regulation of EMT via hnRNP E1

The TGFβ signaling pathway is a critical regulator of cancer progression in part through induction of the epithelial to mesenchymal transition (EMT). This process is aberrantly activated in cancer cells, facilitating invasion of the basement membrane, survival in the circulatory system, and dissemin...

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Detalhes bibliográficos
Publicado no:Cytokine
Main Authors: Howley, Breege V, Howe, Philip H
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063801/
https://ncbi.nlm.nih.gov/pubmed/29396052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2017.12.032
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