Purinergic P2X4 receptors and mitochondrial ATP production regulate T cell migration

T cells must migrate in order to encounter antigen-presenting cells (APCs) and to execute their varied functions in immune defense and inflammation. ATP release and autocrine signaling through purinergic receptors contribute to T cell activation at the immune synapse that T cells form with APCs. Her...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Ledderose, Carola, Liu, Kaifeng, Kondo, Yutaka, Slubowski, Christian J., Dertnig, Thomas, Denicoló, Sara, Arbab, Mona, Hubner, Johannes, Konrad, Kirstin, Fakhari, Mahtab, Lederer, James A., Robson, Simon C., Visner, Gary A., Junger, Wolfgang G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063471/
https://ncbi.nlm.nih.gov/pubmed/29894310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120972
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