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The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling

Pressure overload of the heart leads to cardiac remodeling that may progress into heart failure, a common, morbid and mortal condition. Increased mechanistic insight into remodeling is instrumental for development of novel heart failure treatment. Cardiac remodeling comprises cardiomyocyte hypertrop...

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Veröffentlicht in:PLoS One
Hauptverfasser: Andenæs, Kine, Lunde, Ida G., Mohammadzadeh, Naiyereh, Dahl, Christen P., Aronsen, Jan Magnus, Strand, Mari E., Palmero, Sheryl, Sjaastad, Ivar, Christensen, Geir, Engebretsen, Kristin V. T., Tønnessen, Theis
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063439/
https://ncbi.nlm.nih.gov/pubmed/30052659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201422
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