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Regulating the human HECT E3 ligases

Ubiquitination, the covalent attachment of ubiquitin to proteins, by E3 ligases of the HECT (homologous to E6AP C terminus) family is critical in controlling diverse physiological pathways. Stringent control of HECT E3 ligase activity and substrate specificity is essential for cellular health, where...

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Publicat a:Cell Mol Life Sci
Autors principals: Sluimer, Jasper, Distel, Ben
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063350/
https://ncbi.nlm.nih.gov/pubmed/29858610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-018-2848-2
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