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HECT E3s and human disease

In a simplified view, members of the HECT E3 family have a modular structure consisting of the C-terminal HECT domain, which is catalytically involved in the attachment of ubiquitin to substrate proteins, and N-terminal extensions of variable length and sequence that mediate the substrate specificit...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Scheffner, Martin, Staub, Olivier
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2106370/
https://ncbi.nlm.nih.gov/pubmed/18047743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-8-S1-S6
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