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Developmental Loci Harbor Clusters of Accelerated Regions That Evolved Independently in Ape Lineages

Some of the fastest evolving regions of the human genome are conserved noncoding elements with many human-specific DNA substitutions. These human accelerated regions (HARs) are enriched nearby regulatory genes, and several HARs function as developmental enhancers. To investigate if this evolutionary...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Biol Evol
Egile Nagusiak: Kostka, Dennis, Holloway, Alisha K, Pollard, Katherine S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063267/
https://ncbi.nlm.nih.gov/pubmed/29897475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msy109
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