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The Role of GC-Biased Gene Conversion in Shaping the Fastest Evolving Regions of the Human Genome
GC-biased gene conversion (gBGC) is a recombination-associated evolutionary process that accelerates the fixation of guanine or cytosine alleles, regardless of their effects on fitness. gBGC can increase the overall rate of substitutions, a hallmark of positive selection. Many fast-evolving genes an...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3278478/ https://ncbi.nlm.nih.gov/pubmed/22075116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msr279 |
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