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motifDiverge: a model for assessing the statistical significance of gene regulatory motif divergence between two DNA sequences

Next-generation sequencing technology enables the identification of thousands of gene regulatory sequences in many cell types and organisms. We consider the problem of testing if two such sequences differ in their number of binding site motifs for a given transcription factor (TF) protein. Binding s...

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Dettagli Bibliografici
Pubblicato in:Stat Interface
Autori principali: KOSTKA, DENNIS, FRIEDRICH, TARA, HOLLOWAY, ALISHA K., POLLARD, KATHERINE S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689439/
https://ncbi.nlm.nih.gov/pubmed/26709360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4310/SII.2015.v8.n4.a6
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