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Borders of Cis-Regulatory DNA Sequences Preferentially Harbor the Divergent Transcription Factor Binding Motifs in the Human Genome

Changes in cis-regulatory DNA sequences and transcription factor (TF) repertoires provide major sources of phenotypic diversity that shape the evolution of gene regulation in eukaryotes. The DNA-binding specificities of TFs may be diversified or produce new variants in different eukaryotic species....

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Huang, Jia-Hsin, Kwan, Ryan Shun-Yuen, Tsai, Zing Tsung-Yeh, Lin, Tzu-Chieh, Tsai, Huai-Kuang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261980/
https://ncbi.nlm.nih.gov/pubmed/30524473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00571
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