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ProTide generated long-acting abacavir nanoformulations
Abacavir pronucleotide nanoformulations (NM3ABC) were prepared as a novel long acting slow effective release antiretroviral therapy. Single NM3ABC treatment of human monocyte-derived macrophages produced sustained intracellular carbovir-triphosphate and antiretroviral activities for up to 30 days.
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| Publié dans: | Chem Commun (Camb) |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Royal Society of Chemistry
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6063073/ https://ncbi.nlm.nih.gov/pubmed/29995046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc04708a |
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