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Induction and inhibition of human cytochrome P4501 by oxygenated polycyclic aromatic hydrocarbons

Oxygenated polycyclic aromatic hydrocarbons (oxy-PAHs) are found in the environment together with PAHs. However, less is known concerning their biological activity including their impact on aryl hydrocarbon receptor (AHR) signalling and the subsequent modulation of the cytochrome P450 monooxygenases...

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Detalhes bibliográficos
Publicado no:Toxicol Res (Camb)
Main Authors: Wincent, Emma, Le Bihanic, Florane, Dreij, Kristian
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062249/
https://ncbi.nlm.nih.gov/pubmed/30090389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6tx00004e
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