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Induction and inhibition of human cytochrome P4501 by oxygenated polycyclic aromatic hydrocarbons

Oxygenated polycyclic aromatic hydrocarbons (oxy-PAHs) are found in the environment together with PAHs. However, less is known concerning their biological activity including their impact on aryl hydrocarbon receptor (AHR) signalling and the subsequent modulation of the cytochrome P450 monooxygenases...

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Publicat a:Toxicol Res (Camb)
Autors principals: Wincent, Emma, Le Bihanic, Florane, Dreij, Kristian
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062249/
https://ncbi.nlm.nih.gov/pubmed/30090389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6tx00004e
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