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In silico prediction of chemical genotoxicity using machine learning methods and structural alerts

Genotoxicity tests can detect compounds that have an adverse effect on the process of heredity. The in vivo micronucleus assay, a genotoxicity test method, has been widely used to evaluate the presence and extent of chromosomal damage in human beings. Due to the high cost and laboriousness of experi...

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Bibliografische gegevens
Gepubliceerd in:Toxicol Res (Camb)
Hoofdauteurs: Fan, Defang, Yang, Hongbin, Li, Fuxing, Sun, Lixia, Di, Peiwen, Li, Weihua, Tang, Yun, Liu, Guixia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Royal Society of Chemistry 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062245/
https://ncbi.nlm.nih.gov/pubmed/30090576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7tx00259a
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