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In Silico Prediction of Chemical Toxicity for Drug Design Using Machine Learning Methods and Structural Alerts

During drug development, safety is always the most important issue, including a variety of toxicities and adverse drug effects, which should be evaluated in preclinical and clinical trial phases. This review article at first simply introduced the computational methods used in prediction of chemical...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Chem
Päätekijät: Yang, Hongbin, Sun, Lixia, Li, Weihua, Liu, Guixia, Tang, Yun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826228/
https://ncbi.nlm.nih.gov/pubmed/29515993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00030
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