Sequence, Structure, and Context Preferences of Human RNA Binding Proteins

RNA-binding proteins (RBPs) orchestrate the production, processing, and function of mRNAs. Here we present the affinity landscapes of 78 human RBPs using an unbiased assay that determines the sequence, structure, and context preferences of these proteins in vitro by deep sequencing of bound RNAs. Th...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Dominguez, Daniel, Freese, Peter, Alexis, Maria, Su, Amanda, Hochman, Myles, Palden, Tsultrim, Bazile, Cassandra, Lambert, Nicole J., Van Nostrand, Eric L, Pratt, Gabriel A., Yeo, Gene W., Graveley, Brenton R., Burge, Christopher B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062212/
https://ncbi.nlm.nih.gov/pubmed/29883606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.05.001
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