Deletion of exchange proteins directly activated by cAMP (Epac) causes defects in hippocampal signaling in female mice

Previous studies demonstrate essential roles for the exchange proteins directly activated by cAMP 1 and 2 (Epac1 and Epac2; here collectively referred to as Epac) in the brain. In the hippocampus, Epac contributes to the control of neuronal growth and differentiation and has been implicated in memor...

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Bibliographic Details
Published in:PLoS One
Main Authors: Aesoy, Reidun, Muwonge, Haruna, Asrud, Kathrine S., Sabir, Misbah, Witsoe, Solveig L., Bjornstad, Ronja, Kopperud, Reidun K., Hoivik, Erling A., Doskeland, Stein Ove, Bakke, Marit
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062027/
https://ncbi.nlm.nih.gov/pubmed/30048476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200935
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