Immune-evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury

Chondroitinase ABC is a promising preclinical therapy that promotes functional neuroplasticity after CNS injury by degrading extracellular matrix inhibitors. Efficient delivery of chondroitinase ABC to the injured mammalian spinal cord can be achieved by viral vector transgene delivery. This approac...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Brain
Asıl Yazarlar: Burnside, Emily R, De Winter, Fred, Didangelos, Athanasios, James, Nicholas D, Andreica, Elena-Cristina, Layard-Horsfall, Hugo, Muir, Elizabeth M, Verhaagen, Joost, Bradbury, Elizabeth J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2018
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061881/
https://ncbi.nlm.nih.gov/pubmed/29912283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy158
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