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Chondroitinase gene therapy improves upper limb function following cervical contusion injury

Chondroitin sulphate proteoglycans (CSPGs) are known to be important contributors to the intensely inhibitory environment that prevents tissue repair and regeneration following spinal cord injury. The bacterial enzyme chondroitinase ABC (ChABC) degrades these inhibitory molecules and has repeatedly...

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Bibliografiske detaljer
Udgivet i:Exp Neurol
Main Authors: James, Nicholas D., Shea, Jessie, Muir, Elizabeth M., Verhaagen, Joost, Schneider, Bernard L., Bradbury, Elizabeth J.
Format: Artigo
Sprog:Inglês
Udgivet: Academic Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590527/
https://ncbi.nlm.nih.gov/pubmed/26044197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.05.022
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