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Immune-evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury
Chondroitinase ABC is a promising preclinical therapy that promotes functional neuroplasticity after CNS injury by degrading extracellular matrix inhibitors. Efficient delivery of chondroitinase ABC to the injured mammalian spinal cord can be achieved by viral vector transgene delivery. This approac...
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| Veröffentlicht in: | Brain |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6061881/ https://ncbi.nlm.nih.gov/pubmed/29912283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy158 |
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