Llwytho...

A CRISPR/molecular beacon hybrid system for live-cell genomic imaging

The clustered regularly interspersed short palindromic repeat (CRISPR) gene-editing system has been repurposed for live-cell genomic imaging, but existing approaches rely on fluorescent protein reporters, making sensitive and continuous imaging difficult. Here, we present a fluorophore-based live-ce...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Wu, Xiaotian, Mao, Shiqi, Yang, Yantao, Rushdi, Muaz N, Krueger, Christopher J, Chen, Antony K
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061827/
https://ncbi.nlm.nih.gov/pubmed/29718399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky304
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