Dual tracer tau PET imaging reveals different molecular targets for (11)C-THK5351 and (11)C-PBB3 in the Alzheimer brain

PURPOSE: Several tau PET tracers have been developed, but it remains unclear whether they bind to the same molecular target on the heterogeneous tau pathology. In this study we evaluated the binding of two chemically different tau-specific PET tracers ((11)C-THK5351 and (11)C-PBB3) in a head-to-head...

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Detaylı Bibliyografya
Yayımlandı:Eur J Nucl Med Mol Imaging
Asıl Yazarlar: Chiotis, Konstantinos, Stenkrona, Per, Almkvist, Ove, Stepanov, Vladimir, Ferreira, Daniel, Arakawa, Ryosuke, Takano, Akihiro, Westman, Eric, Varrone, Andrea, Okamura, Nobuyuki, Shimada, Hitoshi, Higuchi, Makoto, Halldin, Christer, Nordberg, Agneta
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2018
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061462/
https://ncbi.nlm.nih.gov/pubmed/29752516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-018-4012-5
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