Comparative binding properties of the tau PET tracers THK5117, THK5351, PBB3, and T807 in postmortem Alzheimer brains

BACKGROUND: The aim of this study was to compare the binding properties of several tau positron emission tomography tracers—THK5117, THK5351, T807 (also known as AV1451; flortaucipir), and PBB3—head to head in the same human brain tissue. METHODS: Binding assays were performed to compare the regiona...

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Dettagli Bibliografici
Pubblicato in:Alzheimers Res Ther
Autori principali: Lemoine, Laetitia, Gillberg, Per-Göran, Svedberg, Marie, Stepanov, Vladimir, Jia, Zhisheng, Huang, Jinghai, Nag, Sangram, Tian, He, Ghetti, Bernardino, Okamura, Nobuyuki, Higuchi, Makoto, Halldin, Christer, Nordberg, Agneta
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725799/
https://ncbi.nlm.nih.gov/pubmed/29229003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-017-0325-z
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