Cortical laminar tau deposits and activated astrocytes in Alzheimer’s disease visualised by (3)H-THK5117 and (3)H-deprenyl autoradiography

Hyperphosphorylated tau protein deposits and, inflammatory processes are characteristic components of Alzheimer disease (AD) pathology. We here aimed to visualize in vitro the distribution of tau deposits and activated astrocytes across the cortical layers in autopsy AD brain tissue using the radiot...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lemoine, Laetitia, Saint-Aubert, Laure, Nennesmo, Inger, Gillberg, Per-Göran, Nordberg, Agneta
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379625/
https://ncbi.nlm.nih.gov/pubmed/28374768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45496
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