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Expansion of gene clusters, circular orders, and the shortest Hamiltonian path problem

Clusters of paralogous genes such as the famous HOX cluster of developmental transcription factors tend to evolve by stepwise duplication of its members, often involving unequal crossing over. Gene conversion and possibly other mechanisms of concerted evolution further obfuscate the phylogenetic rel...

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Détails bibliographiques
Publié dans:J Math Biol
Auteurs principaux: Prohaska, Sonja J., Berkemer, Sarah J., Gärtner, Fabian, Gatter, Thomas, Retzlaff, Nancy, Höner zu Siederdissen, Christian, Stadler, Peter F.
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060901/
https://ncbi.nlm.nih.gov/pubmed/29260295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00285-017-1197-3
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