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Expansion of gene clusters, circular orders, and the shortest Hamiltonian path problem

Clusters of paralogous genes such as the famous HOX cluster of developmental transcription factors tend to evolve by stepwise duplication of its members, often involving unequal crossing over. Gene conversion and possibly other mechanisms of concerted evolution further obfuscate the phylogenetic rel...

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Detalhes bibliográficos
Publicado no:J Math Biol
Main Authors: Prohaska, Sonja J., Berkemer, Sarah J., Gärtner, Fabian, Gatter, Thomas, Retzlaff, Nancy, Höner zu Siederdissen, Christian, Stadler, Peter F.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060901/
https://ncbi.nlm.nih.gov/pubmed/29260295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00285-017-1197-3
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