AKT2 siRNA delivery with amphiphilic-based polymeric micelles show efficacy against cancer stem cells

Development of RNA interference-based therapies with appropriate therapeutic window remains a challenge for advanced cancers. Because cancer stem cells (CSC) are responsible of sustaining the metastatic spread of the disease to distal organs and the progressive gain of resistance of advanced cancers...

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Vydáno v:Drug Deliv
Hlavní autoři: Rafael, Diana, Gener, Petra, Andrade, Fernanda, Seras-Franzoso, Joaquin, Montero, Sara, Fernández, Yolanda, Hidalgo, Manuel, Arango, Diego, Sayós, Joan, Florindo, Helena F., Abasolo, Ibane, Schwartz, Simó, Videira, Mafalda
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060707/
https://ncbi.nlm.nih.gov/pubmed/29667444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1461276
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