AKT2 siRNA delivery with amphiphilic-based polymeric micelles show efficacy against cancer stem cells

Development of RNA interference-based therapies with appropriate therapeutic window remains a challenge for advanced cancers. Because cancer stem cells (CSC) are responsible of sustaining the metastatic spread of the disease to distal organs and the progressive gain of resistance of advanced cancers...

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Bibliographische Detailangaben
Veröffentlicht in:Drug Deliv
Hauptverfasser: Rafael, Diana, Gener, Petra, Andrade, Fernanda, Seras-Franzoso, Joaquin, Montero, Sara, Fernández, Yolanda, Hidalgo, Manuel, Arango, Diego, Sayós, Joan, Florindo, Helena F., Abasolo, Ibane, Schwartz, Simó, Videira, Mafalda
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060707/
https://ncbi.nlm.nih.gov/pubmed/29667444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1461276
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