AKT2 siRNA delivery with amphiphilic-based polymeric micelles show efficacy against cancer stem cells

Development of RNA interference-based therapies with appropriate therapeutic window remains a challenge for advanced cancers. Because cancer stem cells (CSC) are responsible of sustaining the metastatic spread of the disease to distal organs and the progressive gain of resistance of advanced cancers...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Rafael, Diana, Gener, Petra, Andrade, Fernanda, Seras-Franzoso, Joaquin, Montero, Sara, Fernández, Yolanda, Hidalgo, Manuel, Arango, Diego, Sayós, Joan, Florindo, Helena F., Abasolo, Ibane, Schwartz, Simó, Videira, Mafalda
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060707/
https://ncbi.nlm.nih.gov/pubmed/29667444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1461276
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