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The influence of the SULT1A status – wild-type, knockout or humanized – on the DNA adduct formation by methyleugenol in extrahepatic tissues of mice
Methyleugenol, present in herbs and spices, has demonstrated carcinogenic activity in the liver and, to a lesser extent, in extrahepatic tissues of rats and mice. It forms DNA adducts after hydroxylation and sulphation. As previously reported, hepatic DNA adduct formation by methyleugenol in mice is...
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Pubblicato in: | Toxicol Res (Camb) |
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Autori principali: | , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Royal Society of Chemistry
2016
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6060700/ https://ncbi.nlm.nih.gov/pubmed/30090391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5tx00358j |
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