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Hepatoprotective activity of viscosine is mediated by attenuation of hepatic macrophages and iNOS expression in CCl(4)-intoxicated rats

This study investigated the molecular mechanism(s) of the protective effects of a C-alkylated flavonoid, viscosine on an animal model of CCl(4)-induced hepatotoxicity. Viscosine at 20, 50 and 100 mg kg(–1) was orally administered in a dose dependent manner per day for 3 days before the CCl(4) (1 : 1...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Toxicol Res (Camb)
Päätekijät: Ali, Hamid, Kabir, Nurul, Shah, Muhammad Raza, Muhammad, Akhtar, Ali, Safdar, Mehmood, Shahab, Ali, Amjad, Ali, Abid, Jahan, Azra
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Royal Society of Chemistry 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060697/
https://ncbi.nlm.nih.gov/pubmed/30090468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6tx00165c
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