Steroidal Alkaloids as an Emerging Therapeutic Alternative for Investigation of Their Immunosuppressive and Hepatoprotective Potential

The compounds, sarcovagine-D, alkaloid-C, and holaphylline isolated from Sarcococca saligna were found to possess immunosuppressive activities. These compounds were characterized for in vitro inhibition on human T-cells proliferation and IL-2 production. The compounds showed significant immunosuppre...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Jan, Naeem U., Ahmad, Bashir, Ali, Safdar, Adhikari, Achyut, Ali, Amjad, Jahan, Azra, Ali, Abid, Ali, Hamid
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359222/
https://ncbi.nlm.nih.gov/pubmed/28377714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00114
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