Differential hepatoprotective mechanisms of rutin and quercetin in CCl(4)-intoxicated BALB/cN mice

AIM: To investigate the mechanisms underlying the protective effects of quercetin-rutinoside (rutin) and its aglycone quercetin against CCl(4)-induced liver damage in mice. METHODS: BALB/cN mice were intraperitoneally administered rutin (10, 50, and 150 mg/kg) or quercetin (50 mg/kg) once daily for...

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Main Authors: Domitrović, Robert, Jakovac, Hrvoje, Vasiljev Marchesi, Vanja, Vladimir-Knežević, Sanda, Cvijanović, Olga, Tadić, Žarko, Romić, Željko, Rahelić, Dario
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2012
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002705/
https://ncbi.nlm.nih.gov/pubmed/22902988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.62
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