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Supragranular Pyramidal Cells Exhibit Early Metabolic Alterations in the 3xTg-AD Mouse Model of Alzheimer’s Disease

The impairment of cerebral glucose utilization is an early and predictive biomarker of Alzheimer’s disease (AD) that is likely to contribute to memory and cognition disorders during the progression of the pathology. Yet, the cellular and molecular mechanisms underlying these metabolic alterations re...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Piquet, Juliette, Toussay, Xavier, Hepp, Régine, Lerchundi, Rodrigo, Le Douce, Juliette, Faivre, Émilie, Guiot, Elvire, Bonvento, Gilles, Cauli, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060432/
https://ncbi.nlm.nih.gov/pubmed/30072874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00216
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